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The Conference Championship Round of the 2025 NFL Playoffs is on tap for Sunday and will feature a loaded NFL DFS player pool. The Kansas City Chiefs have the opportunity to move one step closer towards becoming the first team in NFL history to win three straight Super Bowl titles when they host the Buffalo Bills in the AFC Championship Game. Kickoff is at 6:30 p.m. ET on CBS and Paramount+. In the NFC Championship Game, the Philadelphia Eagles host the Washington Commanders at 3 p.m. ET. All four teams that will be in action are led by dynamic quarterbacks that are capable of anchoring NFL DFS lineups and NFL DFS stacks.

Josh Allen, Patrick Mahomes, Jalen Hurts, and Jayden Daniels are all dual-threat quarterbacks who have proven to be high-end DFS options. Other players on the Sunday slate that will be popular NFL DFS picks include Saquon Barkley, Terry McLaurin, Travis Kelce, and James Cook. Who should you target when building NFL DFS lineups for the Conference Championship Round on Sunday? Before making any NFL DFS picks for Sunday or locking in NFL DFS lineups on sites like DraftKings and FanDuel, be sure to check out SportsLine's advanced NFL DFS Lineup Optimizer.

The DFS Optimizer uses info from the SportsLine Advanced-Data Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on betting apps like DraftKings and FanDuel. It simulates every game 10,000 times to help DFS players optimize and build winning DraftKings and FanDuel lineups. Optimize, export, and enter lineups confidently with injury updates, floor and ceiling player projections, and Vegas lines and picks all with one winning tool for sports betting apps.

Now, SportsLine's NFL DFS Optimizer has turned its attention to Sunday's Conference Championship in the 2025 NFL playoffs schedule and just locked in its top daily Fantasy football lineups. You can only see its optimal lineups at SportsLine.

Top NFL Conference Championship picks for Sunday

One of the Optimizer's top DFS value picks for Sunday is Eagles wide receiver DeVonta Smith ($5,800 on DraftKings and $7,300 on FanDuel). Smith finished the regular season with 68 catches for 883 yards and eight touchdowns in 13 games, and remains one of the most explosive wide receivers in the NFL today. With fellow Eagles wide receiver A.J. Brown battling a knee injury, Smith could see an uptick of targets in the NFC Championship Game.

The 2020 Heisman Trophy winner caught 10 passes for 80 yards in two regular season games against the Commanders this season, but could be in store for a more productive game on Sunday. Smith leads the Eagles in receptions during the 2025 NFL Playoffs (8), and has career postseason totals of 35 receptions for 481 yards and a touchdown on 53 targets over seven games. Smith has gone over 100 receiving yards in two playoff games over the course of his four-year NFL career. See who else to pick here.

The Optimizer's NFL DFS strategy also includes rostering Chiefs wide receiver Xavier Worthy ($5,500 on DraftKings and $6,500 on FanDuel). The Chiefs traded up, ironically enough with the Bills, to select Worthy with the No. 28 overall pick in the 2024 NFL Draft and despite there being no signs of bad blood between the two franchises besides the Chiefs just continuing to get the better of them in the postseason, it's human nature to imagine Kansas City will try to show off Worthy a little more on this stage and in this matchup. Worthy had four receptions for 61 yards and a touchdown in the regular season against Buffalo, but the Bills exited with a victory.

Andy Reid has become more creative in recent weeks with different ways to use Worthy in the passing and running game. Worthy set an NFL combine record for the 40-yard dash (4.21 seconds) and a quarterback like Patrick Mahomes and a play-caller like Reid can torment teams with speed like that. Worthy had five receptions for 45 yards, finishing only behind Travis Kelce, in the Divisional Round and he's likely to be heavily involved again on Sunday. Worthy was Kansas City's leading pass catcher in two of the final three games the starters played this season. You can see the rest of the Optimizer's NFL DFS picks here.

How to build Sunday Conference Championship NFL DFS lineups

The NFL DFS Optimizer is also targeting multiple undervalued players who could explode for huge numbers on Sunday. Those players could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who they are, and the rest of the Optimizer's NFL DFS picks, at SportsLine

So what is the optimal NFL DFS lineup for Sunday, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice and stacks, all from an NFL DFS Optimizer that simulates every game 10,000 times, and find out.