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The New York Jets and San Francisco 49ers will wrap up the Week 1 NFL schedule when they meet on Monday Night Football. With players like Aaron Rodgers, Deebo Samuel and George Kittle in action, there is no shortage of NFL player props at sportsbooks everywhere. 49ers running back Christian McCaffrey dealt with a calf injury during the preseason and is inactive for MNF. While Samuel does most of his damage as a wide receiver, he is also regularly involved as a rusher, posting double-digit rushing yards in nine of his 15 regular-season games in 2023 and giving you plenty of options for NFL prop bets.

Samuel's over/under for rushing yards is 10.5 in the latest Week 1 NFL odds. He is facing a Jets defense that allowed the eighth-most rushing yards per game last season, and McCaffrey's injury could lead to more touches for Samuel, so should you back him with your Jets vs. 49ers NFL player props? Before betting any NFL props for Monday's action or entering NFL predictions on sites like PrizePicks, Underdog Fantasy, Sleeper Fantasy, or DraftKings Pick6, you need to see the 49ers vs. Jets NFL prop predictions powered by SportsLine's AI PickBot.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each player prop. The AI predictions are determined by statistically learning from each player's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. Last season, the AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. Anybody who followed those picks was way up.

For 49ers vs. Jets betting on Monday Night Football, the AI PickBot has evaluated the NFL player prop odds and provided Jets vs. 49ers prop picks for every available prop market. You can only see the AI player prop predictions for San Francisco vs. New York here.

Top NFL player prop bets for 49ers vs. Jets

After analyzing Jets vs. 49ers props and examining the dozens of NFL player prop markets, the AI PickBot says Jets quarterback Aaron Rodgers goes under 235.5 passing yards. The 40-year-old is coming off a season-ending Achilles injury and has not thrown a touchdown in a season opener since the 2020 campaign. He threw for 133 yards in the 2021 opener and 195 in the 2022 opener before getting hurt several plays into his New York debut last year.

Rodgers averaged 217.4 passing yards per game during his last full season (2022), going under 236.5 yards in 12 of 17 games. He is facing a stout San Francisco defense that had more interceptions (22) than passing touchdowns allowed (20) in 2023, recording the seventh-most sacks (48) of any team in the league. Rodgers is going to have trouble posting big numbers against the 49ers, and the AI PickBot has the veteran finishing with less than 200 passing yards on Monday. See more NFL props here.

How to make NFL player prop bets for New York vs. San Francisco

In addition, the AI PickBot says another star sails past his total and has five other NFL props rated 4 stars or better. You need to see the AI PickBot's analysis before making any 49ers vs. Jets prop bets for Monday Night Football.

Which Jets vs. 49ers prop bets should you target on Monday Night Football? Visit SportsLine now to see the top 49ers vs. Jets props, all from the SportsLine AI PickBot that nailed 1,674 top-rated picks last season.